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Lexapro blocks the re-absorption of serotonin by the first nerve cell. Lexapro is taken orally, as often as indicated in the prescription of your doctor. Lexapro is taken orally, as often as indicated in the prescription of your doctor. Lexapro is taken orally, as often as indicated in the prescription of your doctor. Lexapro is taken orally, as often as indicated in the prescription of your doctor. In the development and severity of depressive symptoms, such as sad mood, fatigue, lack of pleasure, etc. Escitalopram appears to work by increasing the available supply of serotonin, Escitalopram improves symptoms of depression.